Research & News

Factors Associated with MTCT of HIV Despite Optimal Conditions

Jan 31, 2010

The rate of MTCT of HIV-1 among mothers who delivered in the French Perinatal Cohort between 1997 and 2006 was 1.5%. Even when optimal conditions were met-- meaning a term delivery of 37 weeks or more to a mother receiving antiretroviral therapy (ART), with the last... Read More

Multinational Clinical Trial Begins to Determine How Best to Reduce Perinatal HIV Transmission

Jan 31, 2010

On January 15, 2010 a large multinational clinical trial began. The PROMISE (Promoting Maternal-Infant Survival Everywhere) study aims to determine the best way to reduce the risk of HIV transmission from HIV-infected pregnant women to their infants during pregnancy and... Read More

Postpartum Antiretroviral Drug Resistance in HIV-Positive Women

Jan 05, 2010

This study found antiretroviral naive women who received pregnancy-limited antiretroviral therapy to have high rates of postpartum drug resistance . The main determinants of resistance selection during pregnancy were the antiretroviral regimen chosen to prevent perinatal... Read More

Updated DHHS and WHO Guidelines for HIV Treatment Now Available

Dec 07, 2009

The Department of Health and Human Services (DHHS) and the World Health Organization (WHO) recently released updates to their HIV treatment guidelines for adults and adolescents. For information about key updates to the DHHS guidelines, click here. The WHO updates recommend... Read More

Hepatotoxicity in HIV-Infected Pregnant Women on ART

Nov 17, 2009

An analysis of HIV-infected pregnant women on antiretroviral therapy and HIV-infected nonpregnant women from multicenter prospective cohorts demonstrated that pregnancy was significantly associated with hepatotoxicity. There was no significant association between nevirapine... Read More

Short Course AZT/3TC Reduces Nevirapine Resistance

Nov 16, 2009

A study conducted in South Africa demonstrated that a short course of AZT and 3TC following single dose nevirapine in mothers and infants reduced emergent NNRTI resistance mutations. When compared to mothers and infants who received only single dose nevirapine, the... Read More

Breastfeeding With Maternal ARV Therapy in Resource-Limited Settings

Nov 15, 2009

In a study of HIV-infected pregnant women in Rwanda, maternal HAART while breastfeeding was associated with a low risk of postnatal HIV transmission. This risk was similar to the formula feeding cohort. This approach may offer a culturally appropriate alternative to formula... Read More

Need for Improved Integration of STD/HIV and Contraceptive Services

Nov 12, 2009

An analysis of data from a 2002 CDC survey revealed a documented need for improved integration of contraceptive services with STD/HIV services. Investigators estimated that 35% of single young sexually active women who received contraceptive services were not offered... Read More

Impressive Gains in HIV Testing During Pregnancy in a Diverse Insured Population

Nov 12, 2009

This study examined the HIV testing rate in a racially and ethnically diverse insured population delivering at Kaiser Permanente Southern California hospitals from 1997-2006. The rate of HIV testing during this period increased from 77.6% in 1997 to 91% in 2006. Citation:... Read More

Use of the Rapid HIV Test for Third Trimester Screening

Nov 12, 2009

A study conducted in an ambulatory obstetrics and gynecology clinic in Philadelphia, PA revealed that 95% of women agreed to be rescreened with a rapid HIV test in the third trimester of pregnancy. Of the participants, 91% reported the rapid HIV test was less stressful than... Read More