Care and Treatment

The risk of perinatal transmission of HIV can be reduced to less than 1% with proper care and treatment during pre-conception, pregnancy, labor and the newborn period. Call 1-800-439-4079 for real-time expert medical consultation and immediate up-to-date treatment information anytime day or night.

If you are caring for a laboring pregnant patient with HIV, a patient with a positive rapid HIV test in labor or an infant with HIV exposure, see the Hotline's step-by-step recommendations for Illinois.

Guidelines & Best Practices

Federal Guidelines

The United States Public Health Service provides clinical guidelines for the treatment of HIV/AIDS that are continually reviewed and updated by experts in the field. Sources of treatment information for perinatal HIV include the following:

Recommendations for the Use of Antiretroviral Drugs During Pregnancy and Interventions to Reduce Perinatal HIV Transmission in the United States

  • Federally approved guidelines for pre-conceptional, antepartum, intrapartum and postpartum care of pregnant people living with HIV.

Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection

  • Federally approved guidelines for the care of infants and children with HIV exposure or HIV infection.


Illinois 24/7 Perinatal HIV Hotline Best Practices

The Hotline develops best practice resources for Illinois clinicians based on the United States Public Health Service guidelines. 

Hotline Best Practices: Labor & Delivery Care for Pregnant People with HIV and Care of Infants with Perinatal Exposure to HIV

  • Best practice recommendations for labor and delivery care of pregnant people with HIV and their newborns. 

Guidance for Comprehensive Perinatal Care for People Living with HIV

  • A video series featuring comprehensive guidance for all phases of perinatal care for people living with HIV.