Ruptured Membranes and Perinatal HIV Transmission Risk
A prospective study showed that perinatal HIV transmission rates were slightly higher in women who had ruptured membranes for four hours or more (1.9% versus 1% in women with less than 4 hours of rupture). Of the women in the cohort with viral loads less than 1000 copies/mL at delivery, there were no cases of perinatal transmission where membranes had been ruptured up to 25 hours.
Citation: Cotter AM, Brookfield KF, Duthely LM, Quintero VH, Potter JE, O'Sullivan MJ. Duration of membrane rupture and risk of perinatal transmission of HIV-1 in the era of combination antiretroviral therapy. Am J Obstet Gynecol. 2012 Oct 16. pii: S0002-9378(12)01945-X. doi: 10.1016/j.ajog.2012.10.862. [Epub ahead of print]
Abstract
Citation: Cotter AM, Brookfield KF, Duthely LM, Quintero VH, Potter JE, O'Sullivan MJ. Duration of membrane rupture and risk of perinatal transmission of HIV-1 in the era of combination antiretroviral therapy. Am J Obstet Gynecol. 2012 Oct 16. pii: S0002-9378(12)01945-X. doi: 10.1016/j.ajog.2012.10.862. [Epub ahead of print]
Abstract
