Artificial Reproduction Techniques for Conception in Serodiscordant Couples

Serodiscordant couples in which the infected partner is the male have been successful in utilizing sperm washing in combination with other techniques such as intrauterine insemination (IUI) to reduce the risk of HIV transmission to the female partner during conception. A detailed literature review shows this technique to be safe and as successful in achieving pregnancy as ART in non HIV-infected couples. However, research has not yet demonstrated evidence of the safety or efficacy of the use of pre-exposure prophylaxis (PrEP) by the female partner when the male partner has a suppressed viral load.

Vitorino RL et al. Systematic review of the effectiveness and safety of assisted reproduction techniques in couples serodiscordant for human immunodeficiency virus where the man is positive. Fertil Steril 2011 Apr;95:1684-1690.

Original Article (subscription may be required)