Update on Bicillin® L-A Shortage

CDC has learned that the U.S. Food and Drug Administration (FDA) is allowing the temporary importation of Lentocilin© due to the ongoing limited availability and extended recovery of Bicillin® L-A (Penicillin G Benzathine Injectable Suspension, produced by King Pharmaceuticals LLC, a subsidiary of Pfizer). CDC recommends that jurisdictions strongly consider preserving Benzathine Penicillin G (BPG) for treating patients who are pregnant as penicillin is the only recommended treatment for pregnant women and babies with congenital syphilis. Following the recall and due to high levels of syphilis diagnoses in the United States, there is currently a very limited supply of BPG.

CDC Dear Colleague Letter Regarding Bicillin® L-A Update - March 10, 2026