Research/News - 2014

Raltegravir During Pregnancy

Dec 31, 2014

A study of the pharmacokinetics of raltegravir use during pregnancy showed that the medication, when taken twice daily as part of cART, readily crossed the placenta however the median raltegravir area under the curve was reduced by approximately 50% during pregnancy. ... Read More

PrEP for HIV Prevention and Hormonal Contraceptive Use

Dec 26, 2014

The efficacy of preexposure prophylaxis (PrEP) for HIV-1 prevention has been demonstrated amongst serodiscordant couples.  Researchers in this study wanted to determine that couples where the woman (whether HIV-negative or HIV-positive) used the hormonal contraceptive... Read More

Postpartum Antiretrovirals and HIV Transmission Through Breastfeeding

Dec 26, 2014

The Breastfeeding, Antiretrovirals, and Nutrition (BAN) study randomized mother-infant pairs post-delivery to determine whether 28 weeks of triple therapy (for the mother) or daily infant nevirapine was more effective in prevention of HIV transmission through... Read More

Very Early Treatment (VET) to Prevent Infant HIV

Dec 26, 2014

Researchers discuss the feasibility and limitations of very early treatment (VET) for infants perinatally infected with HIV-1, using the Mississippi child as the demonstration case.  VET is highlighted as a possibility for HIV remission for the pediatric population and... Read More

New Series of HIV-specific Prenatal Classes to Begin in January 2015

Dec 05, 2014

The next series of PACPI's HIV-specific prenatal classes have been scheduled for January 2015. Please see the attached flyer for the class and call 312-334-0971 to enroll your clients and patients.  

Intimate Partner Violence and Perinatal HIV Transmission

Nov 30, 2014

Diagnosis of HIV in women can trigger intimate partner violence (IPV) as issues of disclosure to her partner or accusations of unfaithfulness in the relationship arise. Researchers in South Africa found that women who were diagnosed HIV-positive during pregnancy may have... Read More

Preterm Delivery Among Women on ARVs

Nov 14, 2014

Researchers looked retrospectively at delivery records from HIV-positive women who delivered between 1996 and 2010 to determine if use of ARVs during pregnancy contributed to preterm delivery.  These results showed some correlation between the use of ARVs and the... Read More

New Study Tests Early ARVs in HIV-Infected Infants

Nov 03, 2014

The NIH announced that the IMPAACT group will be starting a new clinical trial, IMPAACT P1115, which will look at the administration of HIV ARVs immediately after birth to infected infants can lead to remission of the virus.  This research was prompted by the finding in... Read More

Use of Text Messages to Support Pregnant, HIV-Positive Women Increased Infant Testing

Oct 22, 2014

A randomized controlled trial in sub-Saharan Africa looked at the use of text messaging to keep mothers in care postpartum and increase rates of infant HIV testing. Those women who received text messages during and after pregnancy had significantly higher rates of early... Read More

Perinatal Transmission Higher in Women with Incident HIV

Oct 22, 2014

A meta-analysis done by researchers in Washington found that the pooled perinatal transmission rate was 22.7% among pregnant and postpartum women worldwide with incident HIV, which is 2.8-fold higher than women with chronic HIV infection.  This is significant for the... Read More