In Utero Infections Linked with Increased Risk of Nevirapine Resistance

A recent study of Ugandan infants revealed that in utero HIV infection was the only factor associated with nevirapine resistance detected in infants 6-8 weeks after sdNVP exposure.

Citation:

Church JD, Mwatha A, Bagenda D, Omer SB, Donnell D, Musoke P, Nakabiito C, Eure C, Bakaki P, Matovu F, Thigpen MC, Guay LA, McConnell M, Fowler MG, Jackson JB, Eshleman SH. In utero HIV infection is associated with an increased risk of nevirapine resistance in ugandan infants who were exposed to perinatal single dose nevirapine. AIDS Res Hum Retroviruses. 2009 Jul;25(7):673-7.

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Abstract