Efficacy of 4 Week Program of Neonatal ARVs
Irish researchers showed that a four-week course of infant ARVs was as effective in preventing vertical transmission of HIV as a six-week course. Transmission rate amongst subjects (N=916) was 1.09%. Additionally, if the mother received at least four-weeks of ARVs as well, transmission rate dropped to 0.4% (N=910). This research provides evidence that a more cost-effective, potentially less toxic four-week course of ARV therapy is a reasonable alternative to the standard of care.
Citation:
Ferguson W, Goode M, Walsh A, Gavin P, Butler K. Evaluation of a 4 weeks neonatal antiretroviral prophylaxis as a component of a prevention of mother-to-child transmission program in a resource-rich setting. Pediatr Infect Dis J. 2011 May;30(5):408-12.
Original Article (subscription may be required)
Abstract
Citation:
Ferguson W, Goode M, Walsh A, Gavin P, Butler K. Evaluation of a 4 weeks neonatal antiretroviral prophylaxis as a component of a prevention of mother-to-child transmission program in a resource-rich setting. Pediatr Infect Dis J. 2011 May;30(5):408-12.
Original Article (subscription may be required)
Abstract
