Use of Neonatal AZT for Prevention of Perinatal HIV Transmission
Researchers looked at mother infant pairs to determine the optimal length of neonatal AZT treatment for HIV-exposed infants. In this study researchers put low risk infants on an abbreviated 2 week AZT regimen. In this small cohort, a short neonatal course of medications was as effective as the traditional German course in preventing mother-to-child HIV transmission.
Citation:
Neubert J, Pfeffer M, Borkhardt A, Niehues T, Adams O, Bolten M, Reuter S, Stannigel H, Laws HJ. Risk adapted transmission prophylaxis to prevent vertical HIV-1 transmission: effectiveness and safety of an abbreviated regimen of postnatal oral zidovudine. BMC Pregnancy Childbirth. 2013 Jan 24;13:22.
