Hepatotoxicity in HIV-Infected Pregnant Women on ART

An analysis of HIV-infected pregnant women on antiretroviral therapy and HIV-infected nonpregnant women from multicenter prospective cohorts demonstrated that pregnancy was significantly associated with hepatotoxicity. There was no significant association between nevirapine and liver enzyme elevation regardless of pregnancy status.


Ouyang DW, Shapiro DE, Lu M, Brogly SB, French AL, Leighty RM, Thompson B, Tuomala RE, Hershow RC. Increased risk of hepatotoxicity in HIV-infected pregnant women receiving antiretroviral therapy independent of nevirapine exposure. AIDS. 2009 Nov 27;23(18):2425-30.

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