Vaginal Ring Containing ARVs May Prevent HIV-1 Transmission

Researchers from the MTN-020-ASPIRE Study Team looked at the use of vaginal rings containing dapivirine to determine whether these rings were effective in preventing the transmission of HIV-1 in Africa. This double-blinded, placebo-controlled trial used a monthly vaginal ring to administer antiretroviral medications to women at research sites in four countries in Sub-Saharan Africa. When used consistently, the ring reduced the risk of HIV-1 acquisition over the placebo group.

 

Citation:
Baeten JM, Palanee-Phillips ER, Brown K, et al. Use of a vaginal ring containing dapivirine for HIV-1 prevention in women. N Eng J Med. 2016 Feb 22. [Epub ahead of print]

 

Abstract

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