Seroconversion During Late Pregnancy and Perinatal HIV Transmission

Using mathematical modeling and perinatal HIV transmission rates and feeding practices in South Africa, researchers determined that a significant amount of pediatric HIV is the result of transmission during late pregnancy or breastfeeding from mothers that seroconverted after the initial antenatal HIV test. The results indicate that seroconversion and transmission through breastfeeding need to be addressed more in perinatal HIV prevention programs in order to achieve the elimination of perinatal HIV by 2015.

Citation:
Johnson LF, Stinson K, Newell M, Bland RM, Moultrie H, Davies M, Rehle TM, Dorrington RE & Sherman GG. The contribution of maternal HIV seroconversion during late pregnancy and breastfeeding to mother-to-child transmission of HIV. J Acquir Immune Defic Syndr. 2012 Apr 1;59(4):417-425.

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Abstract