Safety of In-Utero ARV Exposure

A recent study of neurological outcomes in children who are HIV-exposed but uninfected found some increased risk of neurologic abnormalities. These risks were associated with exposure to efavirenz and didanosine. Dolutegravir expsoure showed some suggestive associations that the authors suggest warrant further study.

Citation: Crowell CS, Williams PL, Cenk Y, Dyke RB, Smith R, Chadwick EG, Seage GR, Diperna A, Hazra R, Pediatric HIV/AIDS Cohort Study. Safety of in-utero antiretroviral exposure: Neurologic outcomes in children who are HIV-exposed but uninfected. AIDS. 2020 Jul 15;34(9):1377-1387.

Original Article (subscription may be required)