Resistance to Antiretrovirals in HIV-Infected Pregnant Women

In a study to determine the prevalence of resistance to ARV prior to treatment and its effect on the pregnancy outcome, investigators found that resistance to antiretrovirals was common in antiretroviral-experienced patients, but not in naive women. The study's findings of 14% prevalence of resistance to zidovudine and lamivudine in antiretroviral-experienced women suggests that alternative NRTI are desirable for this group of patients.

Citation:
Weinberg A, Forster-Harwood J, McFarland EJ, Pappas J, Davies JK, Kinzie K, Barr EA, Paul SM, Salbenblatt CR, Soda E, Vazquez A, Levin MJ. Resistance to antiretrovirals in HIV-infected pregnant women. J Clin Virol. 2009 May;45(1):39-42.

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Abstract