Hormonal Contraception and Interactions with ARVs

Publications and pharmaceutical packages were reviewed to determine any contraindications for ARV co-administration with hormonal contraceptive methods (oral contraceptive pills, injectable dept medroxyprogesterone acetate [DMPA], levonorgestrel intrauterine system [LNG-IUS], contraceptive patch, ring and implant). There was some indication from several studies of decreased contraceptive efficacy of the pill when combined with certain ARVs. Conversely, no effects were noted on the efficacy of DMPA or LNG-IUS when combined with ARV usage. There was not enough data available on the patch, ring, or implant to evaluate the interaction. HIV-positive women who are choosing a hormonal contraceptive method should be educated on the possible reduced efficacy of birth control pills when combined with ARVs.


Robinson JA, Jamshidi R, Burke AE. Contraception for the HIV-positive woman: a review of interactions between hormonal contraception and antiretroviral therapy. Infect Dis Obstet Gynecol. 2012;2012:890160.



Original Article