Research & News

Use of Raltegravir to Prevent Perinatal Transmission

Sep 30, 2013

This case report illustrates the use of raltegravir for viral load supression late in pregnancy.  Although safety and pharmacokinetic data are not available for the use of raltegravir in pregnant women, it has been used in limited cases where the patient has multidrug... Read More

HIV-Positive Women and High Rates of Intimate Partner Violence

Sep 30, 2013

Women have a higher risk of HIV infection when affected by intimate partner violence.  In addition, high rates of intimate partner violence amongst HIV-positive women have been linked to poorer health outcomes, including less engagement in HIV care.  Providers should work... Read More

Perinatal HIV Elimination in High Resource Settings

Sep 12, 2013

While much of the focus on elimination of mother-to-child transmission of HIV has been in low resource settings, there is still work to be done in high resource settings. As women are living longer with the help of ART, more HIV-positive women are having children. Providers... Read More

Transfer of ARVs In Utero versus Via Breastfeeding

Aug 31, 2013

Researchers measured levels of ARVs, including lopinavir, ritonavir, and efavirenz, in infants via samples of hair, plasma, and cord blood as well as mother's breastmilk to determine methods of transfer to infants.  Levels were measured at various times postpartum. ... Read More

Safe Conception for Serodifferent Couples

Aug 31, 2013

Providers from the National Perinatal HIV Hotline and Clinicians' Network penned a letter to the editor of the Journal of Acquired Immune Deficiency Syndrome regarding their experiences consulting on reproduction for couples where one person is HIV-positive and one person... Read More

FDA Approves Antibody/Antigen Test

Aug 08, 2013

The FDA announced on August 8th that they had approved the first rapid HIV test to simultaneously detect antibodies for HIV-1 and HIV-2 as well as the HIV-1 p24 antigen. This will allow for additional HIV detection in community settings. The Alere Determine HIV-1/2 Ag/Ab... Read More

Reducing HIV Viral Load in Late Term Pregnant Women

Jul 31, 2013

This article is a case review of three women in the United Kingdom who needed a reduction of their HIV viral load late in pregnancy to ensure a healthy delivery.  Strategies and considerations are discussed in all three cases.  Ultimately, all infants were determined HIV... Read More

Ethics and Implications of Opt-Out HIV Screening for Pregnant Women

Jun 30, 2013

This article is a review of case studies around the use of opt-out HIV screeening for pregnant women.  Authors explored the ethical considerations of this type of screening as compared to opt-in HIV screening, and its potential effect of prevention of mother-to-child... Read More

Exposure to ARVs and Infant Development

Jun 30, 2013

Exposure to antiretroviral medicines during the perinatal period continues to raise questions as to the long-term effects on those exposed infants.  HIV-negative but exposed infants ages 9-15 months were assessed for cognitive development, including language and motor... Read More

Risk of Amniocentesis in Pregnant, HIV-Positive Women

Jun 30, 2013

Researchers looked at the use of amniocentesis in a case review of women with perinatal transmission who recevied an amnio in the second trimester recommend.  Based on their review, they determined that amnio should only be performed when the woman is on HARRT and ideally... Read More

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