Research/News - 2010

Effects of Treatment Interruption After Pregnancy

Mar 01, 2010

Guidelines for treatment of HIV in pregnancy recommend initiation of ARV therapy after the first trimester in all pregnant patients in order to reduce maternal-to-child transmission (MTCT). This therapy is often discontinued after pregnancy if patients do not otherwise meet... Read More

Maternal ART During Pregnancy and Infant Congenital Anomalies

Feb 22, 2010

A study of infants from Argentina and Brazil enrolled in the NISDI Perinatal Study concluded that the prevalence of congenital anomalies after first trimester exposure to ART was similar to that after second and third trimester exposure. Additionally, the prevalence of... Read More

Opt-in Approach to Prenatal HIV Screening Inferior to Opt-out

Feb 22, 2010

A recent study of the opt-in approach to prenatal HIV screening concluded that this approach leads to inferior screening rates when compared to the opt-out approach. With opt-in screening, 29% of women were not screened for HIV during prenatal care and the approach was... Read More

Racial and Ethnic Disparities in Perinatal HIV Infection

Feb 14, 2010

In an analysis of HIV diagnoses among children from 2004-2007, there were declines in the annual rate of diagnosis of perinatal HIV infection for both black and Hispanic children. However, the rate among black children was 23 times higher than the rate among white children... Read More

Factors Related to In-Utero HIV Mother to Child Transmission

Feb 08, 2010

In developing nations, most interventions to prevent HIV-1 MTCT target the transmission that occurs either at the time of delivery or during the infant breast-feeding period. In-utero transmission (transmission that occurs before the baby has been born) accounts for 20-30%... Read More

Hotline Participates in the Society for Maternal-Fetal Medicine Annual Meeting

Feb 04, 2010

The Hotline presented a poster at the annual meeting of the Society for Maternal-Fetal Medicine in Chicago on February 5, 2010. To view the poster entitled "Impact of state-wide Perinatal HIV Hotline on antepartum care linkage and subsequent specialized prenatal care", see... Read More

Dr. Patricia Garcia Appointed to the Presidential Advisory Council on HIV/AIDS

Feb 01, 2010

Dr. Patricia Garcia, medical director of the Illinois Perinatal HIV Hotline, was appointed to the Presidential Advisory Council on HIV/AIDS (PACHA). PACHA provides advice, information, and recommendations to the President through the Secretary of Health and Human Services... Read More

Multinational Clinical Trial Begins to Determine How Best to Reduce Perinatal HIV Transmission

Jan 31, 2010

On January 15, 2010 a large multinational clinical trial began. The PROMISE (Promoting Maternal-Infant Survival Everywhere) study aims to determine the best way to reduce the risk of HIV transmission from HIV-infected pregnant women to their infants during pregnancy and... Read More

Factors Associated with MTCT of HIV Despite Optimal Conditions

Jan 31, 2010

The rate of MTCT of HIV-1 among mothers who delivered in the French Perinatal Cohort between 1997 and 2006 was 1.5%. Even when optimal conditions were met-- meaning a term delivery of 37 weeks or more to a mother receiving antiretroviral therapy (ART), with the last... Read More

Postpartum Antiretroviral Drug Resistance in HIV-Positive Women

Jan 05, 2010

This study found antiretroviral naive women who received pregnancy-limited antiretroviral therapy to have high rates of postpartum drug resistance . The main determinants of resistance selection during pregnancy were the antiretroviral regimen chosen to prevent perinatal... Read More