Exposure to ARVs In Utero and Language Delays

Researchers from the Pediatric HIV/AIDS Cohort Study found no association with exposure to ARVs in utero and language delays for HIV-exposed but negative children overall.  However, in utero exposure to atazanavir showed increased odds of language delays for one-year olds that was not seen in two-year olds.  As a result, further examination of the effect of atazanavir exposure needs to be done.



Rice ML, Zeldow B, Siberry GK, Purswani M, Malee K, Hoffman HJ, Frederick T, Buchanan A, Sirois PA, Allison SM, Williams PL; for the Pediatric HIV/AIDS Cohort Study (PHACS). Evaluation of risk for late language emergence after in utero antiretroviral drug exposure in HIV-exposed uninfected infants. Pediatr Infect Dis J. 2013 Oct;32(10):e406-e413.



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