When is it recommended to give the newborn Nevirapine?

The antiretroviral medications Nevirapine (Viramune) and 3TC (Lamivudine) should be considered for infants at increased risk for infection such as those born to people with a high viral load at the time of delivery or who are diagnosed with HIV at the time of delivery. Also, if the birthing parent did not receive antepartum antiretroviral therapy or their HIV virus is known or suspected to be resistant to AZT, the addition of Nevirapine and 3TC to the newborn should be considered. The decision to dose Nevirapine/3TC is made on a case-by-case basis. Please call the Illinois Perinatal HIV Hotline at 1-800-439-4079 to consult on an individual case and see the Hotline's Best Practices: Labor & Delivery Care for Pregnant People with HIV and Care of Infants with Perinatal Exposure to HIV for detailed information on criteria for determining risk status and corresponding recommendations for antiretrovirals.