Research & News
Antiretroviral Therapy Switch During Pregnancy
Aug 04, 2011
Women who conceived while on ART were more likely to change ART medications if they were on efavirenz at conception or had a detectable viral load. Women planning on conceiving or likely to conceive should work with their physicians in order to determine the correct drug... Read More
Prevention of Perinatal HIV Among Injection Drug Users in the Ukraine
Aug 04, 2011
The Ukraine European Collaborative Study Group followed a cohort of women from 2000-2010 in seven HIV centers in the Ukraine. Comparison of injection drug users (IDUs) with non-IDU women showed lower rates of adherence to HAART, poorer clinical outcomes, and higher rates... Read More
ART Use Can Prevent HIV Transmission to Uninfected Partner
Aug 04, 2011
NIAID study HPTN 052 released early results due to overwhelming success in prevention of HIV transmission among serodiscordant couples. Those HIV-infected individuals that started ART immediately were overwhelmingly more likely to not transmit HIV to the uninfected partner... Read More
HAART During Antenatal Period for Prevention of MTCT in Low Resource Settings
Aug 03, 2011
Duration of HAART during pregnancy has been shown to be most effective in preventing perinatal transmission at a length of at least 13 weeks. Women who were administered HAART for 4 weeks or less had five times the odds of perinatal transmission than those starting at... Read More
HIV Infection in Only One Infant of Dizygotic Twins
Aug 02, 2011
This case study involves dizygotic twins that are discordant for HIV-infection. Mother's viral load 4 weeks prior to delivery was 2140. Mother received IV AZT during labor and infants received AZT, nevirapine, and 3TC. Twin A was homozygous at two HLA loci, while Twin B... Read More
Life Sciences Special Issue on Drug Abuse and Prevention of Perinatal HIV
Jul 31, 2011
This special issue contains numerous articles on the impact of drug abuse on perinatal HIV transmission in both low resource and high resource settings. Original Articles (subscription may be required)
Cost-effectiveness of Perinatal HIV Prevention in Low Resource Setting
Jul 31, 2011
Implementation of WHO recommendations for extended triple therapy during pregnancy and breastfeeding would result in approximately 7700 less cases of perinatal HIV transmission each year in Nigeria. This would result in a cost savings despite the increased cost of... Read More
Safety of Ritonavir-Boosted Atazanavir in Pregnancy
Jul 31, 2011
Researchers looked at atazanavir/RTV (ritonavir-boosted atazanavir) used once daily during the third trimester of pregnancy for prevention of perinatal HIV transmission. The 300/100 mg qd dose proved effective at prevention of perinatal HIV as well as showed no adverse... Read More
PrEP to Prevent HIV During Conception
Jul 31, 2011
Pre-exposure prophylaxis (PrEP) should be considered as an option for serodiscordant couples wishing to conceive since most other options (sperm washing and artifical insemination for example) are not viable options for most couples. Especially in countries where HIV is... Read More
Effectiveness and Safety of Assisted Reproduction for Serodiscordant Couples
Jul 31, 2011
Researchers reviewed numerous study databases to deterimine the efficacy and safety of assisted reproduction (including intrauterine insemination and intracytoplasmic injection, both post-sperm washing) to achieve pregnancy amongst serodiscordant couples where the man was... Read More